課程資訊
課程名稱
慢性病流行病學
Epidemiology of Chronic Disease 
開課學期
112-2 
授課對象
學程  生物統計學程  
授課教師
簡國龍 
課號
PH3014 
課程識別碼
801 32410 
班次
 
學分
2.0 
全/半年
半年 
必/選修
選修 
上課時間
星期一8,9(15:30~17:20) 
上課地點
公衛214 
備註
公衛系流行病學與預防醫學領域專長必修。與于明暉合授
限學士班三年級以上
總人數上限:30人 
 
課程簡介影片
 
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課程概述

二十一世紀慢性病預防及處置已成為重要的包括癌症及心血管疾病的控制,需著重在生活型態相關危險因子的阻介,如何透過初級預防與次級癌檢等流行病學的工具及方法來了解慢性病面向,進一步對慢性病的預防診斷及預後有一方法學上的認識,特此開設此一課程。
課程設計:
1.強調團隊合作, 分組報告及討論
2.文獻研讀及批判, 資料實作, 問題解決
3.案例研究及實際資料處理

The burdens of the non-communicable disease (NCD) among 21st century have a great challenge, and the prevention and management of NCS, such as cancers and cardiovascular diseases, have become an important task, and the intervention of the lifestyle-related risk factors are crucial for the success. How to apply the epidemiological methods to evaluate the programs of primary prevention and secondary prevention, such as health promotion and screening, and to understand the diagnostic tools and prognosis evaluation, we proposed this course.

We designed the class as the following:
1. We emphasize the team work as group, oral presentation and written report, and discussion together,
2. We propose to conduct literature review and critical critique, data management, statistical analyses, and problem solving,
3. We provide case study, real data practice: Translational Research into Community, using the homework and capstone learning
 

課程目標
提供給對流行病學/生物統計/預防醫學課程有興趣的大學部同學選修。以流行病學重要議題和分析方法作深入淺出的介紹,配合電腦軟體操作和資料分析,訓練同學分析處理流行病學實際問題的能力。
此課程的目標:
1.由全球衛生的觀點了解慢性病的現治及重要性 (PHB CC10)
2.慢性流行病學相關研究設計,包括病例對照研究, 世代研究, 橫斷面研究,臨床試驗 (PHB CC10, FD25-26)
3.慢性流行病學篩檢及診斷工具、評估 (PHB FD25-26)
4.基因及環境因子對慢性病的影響及可能的交互作用 (PHB FD53-54)

The course is designed for undergraduate students who are interested in epidemiology/biostatistics/preventive medicine fields, and we provide the introduction of the important issues and analytic methods for the NCD epidemiology, including the computer software work and data analysis, to train the students in data analysis and problem solving,

At the end of the course the students are expected to
1. Understand the current status and burdens of NCD from the global health viewpoint (PHB CC10),
2. Understand the study designs of NCD, including case-control study, cohort study, cross-sectional study and randomized clinical trial (PHB CC10, FD25-26).
3. Apply the tools for screening and diagnosis of the NCD (PHB FD25-26),
4. Understand the roles of genetics and environmental factors for the NCD, and the potential interactions for the risk of NCD (PHB FD53-54)
 
課程要求
具備基礎流行病學及生物統計學相關知識技術之能力
The basic knowledge in epidemiology and biostatistics is necessary 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
 
參考書目
Patrick L. Remington, Ross C. Brownson, Mark V. Wegner: Chronic disease epidemiology and control, 3rd edition, Washington, D.C. : American Public Health Association, c2010,
e-library in NTU Library: http://tulips.ntu.edu.tw/search~S5*cht?/XChronic+Disease+Epidemiology+and+Control%2C+3rd+Edition&searchscope=5&SORT=D/XChronic+Disease+Epidemiology+and+Control%2C+3rd+Edition&searchscope=5&SORT=D&SUBKEY=Chronic+Disease+Epidemiology+and+Control%2C+3rd+Edition/1%2C32000%2C32000%2CB/frameset&FF=XChronic+Disease+Epidemiology+and+Control%2C+3rd+Edition&searchscope=5&SORT=D&2%2C2%2C
Gordis L: Epidemiology, 2nd edition, W.B. Saunder, 2000 ISBN 0-7216-8338-X
Szklo M and Nieto FJ: Epidemiology, Beyond the basics. Jones and Bartlett Publishers, 2007 ISBN 0-7637-2927-2 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
100% 
Understand the chronic disease epidemiology contents, (1) Midterm report: students should conduct the individual study on specific epidemiological issues, including study design, study analysis and result report (PHB C10, FD25-26). IN addition, students should perform the group presentations in specific homework (PHB FD25-26, FD53-54) 2. Capstone learning, including case study, real data practice: Translational Research into Community, through the homework, oral presentation, and written report. The in-class discussion is also emphasized (PHB FD25-26).  
 
課程進度
週次
日期
單元主題
第1週
2/19  Current Issues and Challenges in Chronic Disease Control 慢性病防治的當前議題與挑戰 于明暉老師 
第2週
2/26  Introduction of Methods in Chronic Disease Epidemiology慢性病流行病學方法概論 于明暉老師 
第3週
3/4  Identification of risk factors: interaction and dose-response relationship (2-1) 鑑定危險因子: 交互作用與劑量效應關係(2-1) 于明暉老師 
第4週
3/11  Identification of risk factors: interaction and dose-response relationship (2-2) 鑑定危險因子: 交互作用與劑量效應關係(2-2)于明暉老師 
第5週
3/18  Risk evaluation and predictive model (2-1) 風險評估與預測模式(2-1)于明暉老師 
第6週
3/25  Risk evaluation and predictive model (2-2) 風險評估與預測模式(2-2)于明暉老師 
第7週
4/1   Population-based survey: estimation of disease burden (2-1) 一般人口調查: 估計疾病負擔(2-1) 于明暉老師 
第8週
4/8   Population-based survey: estimation of disease burden (2-2) 一般人口調查: 估計疾病負擔(2-2) 于明暉老師
[期中考試開始(至4月12日止)
 
第9週
4/15   Issues for epidemiological application in public health and medicine: risk estimate, inference, bias (2-1) 流病方法用在公共衛生與醫學研究議題:危險做計推論及偏差 (2-1)簡國龍老師 
第10週
4/22   Issues for epidemiological application in public health and medicine: risk estimate, inference, bias (2-2) 流病方法用在公共衛生與醫學研究議題:危險做計推論及偏差 (2-2)簡國龍老師 
第11週
4/29   Chronic Disease Surveillance & Diagnosis: Surveillance/Screening (idi/nri/roc) (2-1) 慢性疾病監測及診斷:監測/篩檢工具(idi/nri/roc)(2-1)簡國龍老師 
第12週
5/6   Chronic Disease Surveillance & Diagnosis: Surveillance/Screening (idi/nri/roc) (2-2) 慢性疾病監測及診斷:監測/篩檢工具(idi/nri/roc)(2-2)簡國龍老師 
第13週
5/13   Intervention Methods for Chronic Disease Control (clinical/intervention trial, From community to clinical medicine) (2-1) 慢性疾病防治之阻介計畫:臨床試驗/阻介研究,由社區到臨床醫學(2-1)簡國龍老師 
第14週
5/20   Intervention Methods for Chronic Disease Control (clinical/intervention trial, From community to clinical medicine) (2-2) 慢性疾病防治之阻介計畫:臨床試驗/阻介研究,由社區到臨床醫學(2-2)簡國龍老師 
第15週
5/27   Genetic Epidemiology for Chronic Diseases慢性疾病之遺傳流行病學簡國龍老師 
第16週
6/3   Capstone Learning in Stroke Example綜合頂石學習:以腦中風為例 簡國龍老師[期末考試開始(至6月7日止)]